Chemotherapy of experimental Besnoitia besnoiti infection in rabbits.
نویسندگان
چکیده
Rabbits were infected with a bovine strain of Besnoitia besnoiti parasites derived from VERO cell cultures. Oxytetracycline, given at 30 mg/kg i.m. simultaneously with infection, prevented the development of orchitis. The controls received no treatment. All infected animals showed a transient febrile reaction. It is concluded that oxytetracycline has some therapeutic potential against Besnoitia besnoiti and that rabbits are suitable models for therapeutic trials.
منابع مشابه
The artificial transmission of Besnoitia besnoiti (Marotel, 1912) from chronically infected to susceptible cattle and rabbits.
Besnoitia besnoiti was first described by Besnoit & Robin (1912), who observed the thick-walled parasitic cysts in the skin of a chronically infected cow in Southern France. The crescentic organisms within the cysts, which they called spores, will be referred to as cyst forms or cyst organisms in this discussion , in contradistinction to proliferative forms which are encountered in macrophages ...
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BIGALKE, R. D ., SCHOEMAN, J. H . & McCULLY, R. M ., 1974. Immunization against bovine besnoitiosis with a live vaccine prepared from a blue wildebeest strain of Besnoitia besnoiti grown in cell cultures. 1. Studies on rabbits. Onderstepoort J. vet. Res. 41, 16 (1974). The immunizing potency of a live vaccine prepared from a strain of Besnoitia besnoiti isolated from blue wildebeest and stored ...
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Background: Besnoitiosis caused by Besnoitia besnoiti is regarded as a re-emerging disease in cattle because of the increased number of cases and geographical distribution in many European countries. Aims: The present study was conducted to determine the presence of B. besnoiti in cattle in the Eastern and Southeastern Anatolia of Turkey. <str...
متن کاملObservations on the pathogenesis of bovine and antelope strains of Besnoitia besnoiti (Marotel, 1912) infection in cattle and rabbits.
BASSON , P. A., McCULLY, R. M. & BIGALKE, R. D. Observations on the pathogenesis of bovine and antelope strains of Besnoitia besnoiti (Marotel, 1912) infection in cattle and rabbits. Onderstepoort f . vet. R es. (1970), 37 (2), 105126. Histopathological studies were made on cattle and rabbits, artificially infected with either proliferative organisms of low and high passage level bovine strains...
متن کاملQuantitative real time polymerase chain reaction assays for the sensitive detection of Besnoitia besnoiti infection in cattle.
Bovine besnoitiosis, an economically important disease in cattle in some countries of Africa and Asia, is emerging in Europe. The definitive host of Besnoitia besnoiti, the causative agent of bovine besnoitiosis, is unknown and the transmission of the parasite is not completely understood. Sensitive and quantitative DNA detection methods are needed to determine whether serologically positive an...
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ورودعنوان ژورنال:
- The Onderstepoort journal of veterinary research
دوره 52 4 شماره
صفحات -
تاریخ انتشار 1985